Support with EPIDIOLEX

When you become a member of the EPIDIOLEX support program, you’ll receive practical tools, tips, and information.

  • Get your EPIDIOLEX travel case

  • Stay on track

  • Hear from fellow caregivers



The EPIDIOLEX® Copay Savings Program

Eligible* commercially insured patients may pay as low as $0 per prescription

*Eligibility criteria:

  • A legal resident of the United States or Puerto Rico

  • Commercially insured (patients are not eligible for this program if they are receiving prescription reimbursement for EPIDIOLEX under Medicare Part D, Medicaid, Medigap, VA/DoD (Tricare) programs, the Indian Health Service, or any other federal or state-funded healthcare program, or where prohibited by law)

This offer is subject to change or discontinuation at any time without notice. Other restrictions, including annual maximum limits, may apply. See below for full terms and conditions. No enrollment is required. Eligibility is assessed as part of the standard benefit investigation process performed by the pharmacy. Any copay benefit will be automatically deducted from the patient’s copay. The copay savings program is not prescription coverage or insurance. Patients cannot seek reimbursement from health insurance or any third party for any part of the benefit received by the patient through this program.

EPIDIOLEX® (cannabidiol) Copay Savings Program Card

Savings made simple. Because you worry about enough.

If you or your loved one has been prescribed EPIDIOLEX, make sure to ask your specialty pharmacy if you are eligible for the EPIDIOLEX® Copay Savings Program.

Download our copay savings sheet below for more information. We’re committed to making this process as simple as possible, because you have enough on your plate.


See full terms and conditions. For more information, call 1-833-GBNGAGE/1-833-426-4243. Customer service associates are available Monday through Friday, 8:00 AM – 8:00 PM ET (excluding holidays).

EPIDIOLEX patient & caregiver tools

Tools that help support your experience with EPIDIOLEX, including step-by-step instructions, worksheets, and resources for school and travel.

EPIDIOLEX® (cannabidiol) Medication Guide and FAQs

Getting started with EPIDIOLEX

This brochure contains all you need to know to start the conversation with your healthcare provider.


EPIDIOLEX® (cannabidiol) Medication TSA Travel Card

Traveling with EPIDIOLEX

According to the TSA, this medicine has now been cleared for takeoff everywhere in the US. Before you go, make sure you carry a copy of this travel document. And if you haven't already, click the link below to get your free travel case.

EPIDIOLEX® (cannabidiol) School Nurse Dosing Letter

School nurse letter

Share this letter with the nurse at your child’s school to help make sure your child doesn’t miss a dose of EPIDIOLEX.


Dosing & titration worksheet

Use this calendar as you start EPIDIOLEX and work toward your target dose.

EPIDIOLEX® (cannabidiol) Dosing, Instructions and Medication List

Medication list

List all medications, dosages, and instructions in one convenient place.

EPIDIOLEX® (cannabidiol) Copay Savings Sheet

Copay savings sheet


Learn more about EPIDIOLEX

Information about the medicine, the company that makes it, CBD, EPIDIOLEX FDA approval, and a doctor discussion guide.

About EPIDIOLEX® (cannabidiol), FDA Approved Prescription CBD

Considering EPIDIOLEX?

All about the first-and-only FDA-approved prescription CBD to treat seizures associated with LGS, Dravet syndrome, and TSC.

About Cannabinoids and Cannabidiol in EPIDIOLEX®

Cannabinoids 101: Understanding CBD

An in-depth exploration of cannabidiol, the active ingredient in EPIDIOLEX.

EPIDIOLEX® (cannabidiol) Doctor Discussion Guide for Patients

Doctor Discussion Guide

Questions to help you have a meaningful conversation with your doctor about treatment with EPIDIOLEX.

Información De Prescripción Completa Para EPIDIOLEX (cannabidiol) en solución oral

Información De Prescripción Completa Para EPIDIOLEX (cannabidiol) en solución oral

EPIDIOLEX® (cannabidiol) FAQs


See below for answers to commonly asked questions.

EPIDIOLEX is an FDA-approved medicine containing purified cannabidiol made from plants. It is indicated for the treatment of seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 1 year of age and older.

EPIDIOLEX is an oral solution that is taken twice daily. It should be administered consistently with respect to meals.

EPIDIOLEX may interact with some seizure medicines or other medicines you are taking. Do not start or stop other medicines without talking to your doctor. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and cannabis-based products.

You and your healthcare provider will decide if EPIDIOLEX is the right option.

This may depend on diagnosis and your response to current treatment.

Your healthcare provider may order blood tests and consider medicines and supplements you are currently taking, as well as other risk factors. See the Medication Guide for additional details.

If necessary, EPIDIOLEX can be administered via a feeding tube, such as a nasogastric tube (NG-tube) or gastrostomy tube (G-tube). Do not use with tubes made of polyvinyl chloride (PVC).

EPIDIOLEX has flexible dosing.

When starting EPIDIOLEX, your doctor may begin with a lower dose and slowly increase the amount of medicine to reach the dose he or she believes is right for you.

Once that dose is reached, your doctor will evaluate your response.

If needed, your doctor may adjust your dose based on your response to EPIDIOLEX and whether you are experiencing side effects.

Your doctor may also request blood work to evaluate liver function before you start and during treatment.

You should take EPIDIOLEX exactly as your doctor tells you. Do not stop taking EPIDIOLEX without first talking to your doctor. Stopping a seizure medicine suddenly can cause serious problems.

Be sure to tell your doctor if you are taking any other medicines so he or she can take that into account when creating your EPIDIOLEX dosing schedule.

EPIDIOLEX is made without sugar to be compatible with most epilepsy diets, such as the ketogenic diet. However, always talk to your doctor about your dietary therapy or any changes to dietary therapy before taking EPIDIOLEX.

The most common side effects of EPIDIOLEX include increase in liver enzymes, sleepiness, decreased appetite, diarrhea, fever, vomiting, feeling very tired and weak, rash, sleep problems, and infections.

For a discussion guide with questions that can help you have a thoughtful and productive conversation with your doctor, download the Doctor Discussion Guide.

Your doctor will decide if EPIDIOLEX is right for you or your loved one and write a prescription to be filled at a specialty pharmacy that works with your insurance.

Specialty pharmacies offer expertise in the support and fulfillment of prescriptions for rare, complex, and/or chronic diseases and are like any other pharmacy where you fill FDA-approved prescription medicines. The specialty pharmacy will call you to discuss important information about your prescription, so keep an eye out for a call from a 1-800 number and be sure to check your voicemail.

The medicine is typically shipped directly to your home, and in some cases, you may be able to pick up your prescription from a local pharmacy. Most people receive their first bottle of EPIDIOLEX less than 12 days after their doctor prescribes it.

EPIDIOLEX is an FDA-approved medicine, which means you can only get it through a doctor's prescription.

While studies were not designed to prove how long it takes EPIDIOLEX to work, an exploratory analysis conducted after the studies were complete suggests that some patients with LGS had fewer drop seizures* after using EPIDIOLEX for 8 days, some patients with Dravet syndrome started having fewer convulsive seizures as early as 10 days after starting EPIDIOLEX, and some patients with TSC had fewer TSC-associated seizures after using EPIDIOLEX for 6 days. But everyone's symptoms can be different, so your experience with EPIDIOLEX may be different, too.

*Drop seizures included tonic, atonic, and tonic-clonic that led, or could have led, to a fall or injury.

Convulsive seizures included tonic, tonic-clonic, atonic, and clonic.

TSC-associated seizures included different types of partial onset (focal) seizures and generalized seizures.

The ingredients that make up EPIDIOLEX include cannabidiol (CBD), sesame seed oil, sucralose (an artificial sweetener), alcohol, and strawberry flavor. Alcohol is added to dissolve the sucralose, which is added for flavor and to ensure that EPIDIOLEX ingredients are compatible with the ketogenic diet.

Dairy products are not used in the manufacturing of EPIDIOLEX.

EPIDIOLEX does not contain gluten (wheat, barley, or rye).

EPIDIOLEX is an oral solution of cannabidiol (100 mg/mL) in sesame seed oil. It is important to note that sesame is a seed, not a nut, so if you're allergic to one, you may not be allergic to the other. Sesame seed allergies have been estimated to affect 0.1% of the general population in the US. Nut allergies are more common and may affect 1.4% of the population. EPIDIOLEX should be avoided in patients with a known or suspected sesame seed allergy.

EPIDIOLEX will not make you feel "high," the common effect associated with THC. EPIDIOLEX and THC are entirely different from each other and have different effects on the body.

EPIDIOLEX is an FDA-approved prescription medicine and is therefore legal under federal law. Keep your prescription inside your travel case so it’s always nearby should anyone need to see it.

EPIDIOLEX is recognized by the Transportation Security Administration (TSA) as an FDA-approved cannabis-derived medicine, which means you can legally carry it on airplanes anywhere in the US. For information about traveling with EPIDIOLEX, including rules and regulations, tips for navigating airport security, and useful contact numbers, download a travel card. Join the EPIDIOLEX support program and receive a free travel case to help make sure your EPIDIOLEX stays safe and secure wherever you go.

When your doctor prescribes EPIDIOLEX, he or she will submit the prescription to the specialty pharmacy that works with your insurance to determine coverage. You will probably receive a call from the pharmacy (look out for a 1-800 number) or your healthcare provider to get any information needed to finish filling your prescription. Once your coverage has been approved, the medicine will be shipped directly to your home for free. The aim is to get your prescription filled as quickly as possible, but this may take some time.

There is a robust support program for patients taking EPIDIOLEX. It includes the EPIDIOLEX® Copay Savings Program, help with taking EPIDIOLEX, and advice for living with LGS, Dravet syndrome, or TSC. For more information and to sign up, go to


Advocacy groups

There are many organizations that provide condition-related educational information, support, and useful tools for the community. Visit the sites of these key organizations to learn more.

Tuberous Sclerosis Alliance Logo
Dravet Syndrome Foundation Logo
Child Neurology Foundation Logo
Citizens United for Research in Epilepsy (CURE) Logo
LGS (Lennox-Gastaut Syndrome) Foundation Logo
Epilepsy Foundation Logo

Full terms and conditions

Eligible patients may pay as low as $0 per EPIDIOLEX prescription. Annual maximum limits may apply. The copay savings program is only available for residents of the United States or Puerto Rico with a domestic mailing address (no P.O. boxes) who have commercial insurance coverage with out-of-pocket expenses, including copayments, co-insurance, and deductibles. The copay savings program is not valid for beneficiaries of Medicare, Medicaid, VA/DoD (Tricare) programs, the Indian Health Service or other federal or state healthcare programs, if patient pays for prescription in cash or if patient chooses not to use their insurance coverage. The copay savings program requires a valid, signed prescription for EPIDIOLEX. The pharmacy will bill patient’s insurance for the portion that patient’s insurance plan has agreed to cover. The copay savings program is not health insurance. The pharmacy, patient, or prescriber cannot submit a claim for reimbursement under any federal, state, or other governmental programs or to any third party for any part of the benefit received by the patient through the copay savings program. By using this offer, patients or their representative certify that they will comply with any terms of their health insurance contract requiring notification to their payer of the existence and/or value of this offer. It is illegal to (or offer to) sell, purchase, or trade this offer. This offer is non-transferrable. This offer is void where prohibited by law. No purchase necessary. Copay savings program benefits may not be applied retroactively. If patient’s insurance changes, the pharmacy must be notified immediately. Based on patient’s insurance change, patient may no longer be able to participate in the copay savings program. Jazz Pharmaceuticals reserves the right to terminate or modify this program at any time and without notice and in its sole discretion. In administering the copay savings program, Jazz Pharmaceuticals will process patient’s personal information in accordance with Jazz Pharmaceuticals’ Privacy Policy, which can be found at

For more information, call 1-833-GBNGAGE/1-833-426-4243. Customer service associates are available Monday through Friday, 8:00 AM – 8:00 PM ET (excluding holidays).