Starting on EPIDIOLEX

Now that you’ve been prescribed EPIDIOLEX, you’re probably eager to get started. Here’s what comes next.

EPIDIOLEX cannabidiol travel case

Checking if EPIDIOLEX is covered by insurance

Download a printable guide that highlights the steps you need to take to receive EPIDIOLEX after it is prescribed.


Your doctor and staff will submit your prescription

Your doctor and staff will submit your prescription. It will be sent to the specialty pharmacy that works with your insurance to determine coverage.

Cell phone icon for EPIDIOLEX cannabidiol shipment

You will probably get a call from the pharmacy (look out for a 1-800 number or a local number). You may not recognize the phone number, but it’s important to answer the phone when the pharmacy calls to avoid delays with your EPIDIOLEX shipment. Be sure to have your insurance and prescription information handy when the pharmacy calls. You can also talk to your specialty pharmacy about the best way to communicate (phone, email, or text).

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Once your insurance coverage is confirmed, the prescription will be filled and the medicine will be shipped directly to your home. The aim is to get your prescription filled and delivered to you as quickly as possible, but this may take some time.


EPIDIOLEX availability

Specialty pharmacies have expertise in preparing and filling medicines like EPIDIOLEX. They fill FDA-approved prescriptions just as traditional pharmacies do. Certain specialty pharmacies can ship your medicine to a local store for pickup. If you are interested in this option, talk to your specialty pharmacy to find out more.

Taking EPIDIOLEX for the first time

Use this worksheet to keep track as you start EPIDIOLEX and work toward the dose that’s right for you.


Medicine bottle with syringe

EPIDIOLEX is an oral solution that is taken twice daily. Food may affect EPIDIOLEX levels, so be sure to take EPIDIOLEX consistently with or without food.

You should take EPIDIOLEX cannabidiol exactly as your doctor tells you

You should take EPIDIOLEX exactly as your doctor tells you. Do not stop taking EPIDIOLEX without first talking to your doctor. Stopping an antiseizure medicine suddenly can cause serious problems.

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Your doctor may adjust your dose based on your response to EPIDIOLEX and whether you are experiencing side effects.

Tell your doctor if you are taking any other medicines when creating your dosing schedule

Be sure to tell your doctor if you are taking any other medicines so he or she can take that into account when creating your dosing schedule.

Your doctor may do blood work to evaluate liver function before you start and during treatment

Your doctor may also request blood work to evaluate liver function before you start and during treatment.

EPIDIOLEX dosing explained

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When starting EPIDIOLEX, your doctor may begin with a lower dose and slowly increase the amount of medicine to reach the dose he or she believes is right for you.

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Once that dose is reached, your doctor will evaluate your response.

EPIDIOLEX cannabidiol dosing

If needed, your doctor may adjust your EPIDIOLEX dosing further.


EPIDIOLEX preparation and administration

Taking EPIDIOLEX can be easy if you follow a few simple instructions. View the videos below to watch an experienced caregiver give EPIDIOLEX to his son, or read the Instructions for Use.

Setting up and preparing to administer EPIDIOLEX cannabidiol


Setting up and preparing to administer EPIDIOLEX. Disponible en Español

Instructions for taking EPIDIOLEX cannabidiol or giving it to a loved one

Administering EPIDIOLEX EN ES

Step-by-step instructions for taking EPIDIOLEX or giving it to a loved one. Disponible en Español

EPIDIOLEX cannabidiol syringe and plunger cleaning up

Cleaning up EN ES

How to clean and store the syringe and plunger after each use. Disponible en Español